Inhibition parameters for the A and B isozymes of arylesterase. Results are expressed as pC50 = - log C50, where C50 denotes the inhibitor concentration (in mol/L) giving 50% inhibition.
| Solvent | pC50 (A) | pC50 (B) |
|---|---|---|
| Acetone | 1.19 | 1.09 |
| Acetonitrile | 0.46 | 0.40 |
| Dimethylacetamide | 1.61 | 1.61 |
| Dimethylformamide | 1.44 | 1.53 |
| Dimethylsulfoxide | 0.83 | 0.75 |
| Dioxan | 1.16 | 1.09 |
| Ethyl acetate | 1.02 | 0.95 |
| Hexamethylphosphoramide | 2.38 | 2.34 |
| Nitromethane | 1.26 | 1.27 |
| Propylene carbonate | 1.87 | 2.07 |
| Tetrahydrofuran | 1.94 | 1.93 |
| Triethylphosphate | 2.04 | 2.06 |